To enable analyzes of small volume blood samples (~100 microliters) from newborn children and pediatric patients, senior team member dr Jaromir Mikes developed a whole blood cell stabilizer solution which is now commercially available through a spin-off company, Cytodelics.

To optimize experimental workflows, minimize costs and ensure full traceability of protocols, procedures and reagents used, the Brodin lab senior developer dr Yang Chen has developed several novel applications which integrate seamlessly into a Smart lab framework. We gather clinical data in GDPR compliant databases and integrate these with generated lab data across all projects, all samples analyzed and every reagent consumed.

A challenge in human immunology is to mechanistically investigate cellular processes suggested by observations in patient samples. To enable such mechanistic experiments we develop detailed in vitro systems based on whole blood cultures or lymphoid organoids. Our high-throughput experimental system enables both broad and deep interrogation of signalling pathways, cell-cell interactions and immunomodulatory interventions.